مهندسی سیستم و بهره‌وری

مهندسی سیستم و بهره‌وری

طراحی شبکه زنجیره تأمین سبز و حلقه بسته محصولات دارو با استفاده از الگوریتم جستجوی فاخته

نوع مقاله : پژوهشی

نویسندگان
مرضیه مظفری 1
جعفر سواری 2
1 نویسنده مسئول: استادیار، گروه مهندسی صنایع، واحد تهران جنوب، دانشگاه آزاد اسلامی، تهران، ایران
2 کارشناسی ارشد، گروه مهندسی صنایع، واحد تهران جنوب، دانشگاه آزاد اسلامی، تهران، ایران
10.22034/sep.2025.2050452.1248
چکیده
شرکت‌های داروسازی به دلیل الزامات نظارتی داخلی، ملی و بین‌المللی و همچنین محدودیت‌های تحمیل‌شده توسط دولت‌ها در زمینه‌هایی نظیر تأمین مواد اولیه، توزیع، نرخ ارز، و شرایط تولید و نگهداری، با چالش‌های پیچیده‌ای در طراحی و مدیریت زنجیره تأمین خود روبه‌رو هستند. طراحی شبکه زنجیره تأمین سبز و حلقه بسته می‌تواند نقش کلیدی در کاهش هزینه‌ها، افزایش کارایی، و کاهش اثرات زیست‌محیطی این صنعت ایفا کند. در این مقاله، مدلی برای طراحی شبکه زنجیره تأمین سبز و حلقه بسته محصولات دارویی ارائه‌شده است که به بررسی مکان‌یابی بهینه مراکز تولید، توزیع، و بازیافت می‌پردازد. مدل پیشنهادی عوامل درون‌سازمانی مانند انتخاب مواد اولیه و فناوری‌های سبز و عوامل بیرونی نظیر مکان‌یابی بهینه و بهینه‌سازی سیستم حمل‌ونقل را در نظر می‌گیرد. هدف این مدل، کاهش هزینه‌های ثابت و جاری، کاهش انتشار آلاینده‌های زیست‌محیطی، و بهبود پایداری زنجیره تأمین است. برای حل مسئله، از مدل‌سازی ریاضی در نرم‌افزار GAMS و الگوریتم فرا ابتکاری جستجوی فاخته (CSA) در نرم‌افزار MATLAB استفاده شده است. این رویکرد با ارائه راه‌حل‌های بهینه و کارآمد برای مسائل پیچیده، نتایج قابل اتکایی به دست داده است. یافته‌های این پژوهش نشان می‌دهد که رویکرد پیشنهادی می‌تواند نقش مهمی در بهبود عملکرد و سبز سازی زنجیره تأمین دارو داشته باشد.

تازه های تحقیق

  • ارائه یک مدل ریاضی چندهدفه جهت مسئله طراحی زنجیره تأمین حلقه بسته سبز
  • در نظرگیری برگشت کالا به‌صورت فسادپذیری و فراخوان داروهای دارای عوارض جانبی در زنجیره تأمین محصولات دارویی
  • طراحی الگوریتم جستجوی فاخته جهت حل مدل چندهدفه در ابعاد بزرگ

کلیدواژه‌ها
طراحی شبکه زنجیره تأمین حلقه بسته
محصولات دارویی
بازگشت کالا
زنجیره تأمین سبز
الگوریتم جستجوی فاخته
موضوعات

عنوان مقاله English

Designing a Green Closed-Loop Supply Chain Network for Pharmaceutical Products Using Cuckoo Search Algorithm

نویسندگان English

Marzieh Mozafari 1
Jafar Savari 2
1 Corresponding author: Assistant Professor, Department of Industrial Engineering, South Tehran Branch, Islamic Azad University, Tehran, Iran
2 M.Sc., Department of Industrial Engineering, South Tehran Branch, Islamic Azad University, Tehran, Iran
چکیده English

Pharmaceutical companies face complex challenges in designing and managing their supply chains due to regulatory requirements at the national, international, and internal levels, along with government-imposed constraints such as the sourcing of raw materials, distribution, exchange rates, and production and storage conditions. Designing green and closed-loop supply chain networks can play a crucial role in reducing costs, increasing efficiency, and minimizing the environmental impact of the industry. In this paper, a model for designing green and closed-loop supply chains for pharmaceutical products is proposed, focusing on the optimal location of production, distribution, and recycling centers. The proposed model takes into account both internal factors, such as the selection of raw materials and green technologies, and external factors like optimal site selection and transportation system optimization. The goal of this model is to minimize fixed and operational costs, reduce environmental pollutant emissions, and enhance supply chain sustainability. To solve the problem, mathematical modeling was applied using GAMS software, and the Cuckoo Search Algorithm (CSA) was implemented in MATLAB software. This approach provides optimal and efficient solutions for complex problems, yielding reliable results. The findings of this research indicate that the proposed approach can play a significant role in improving performance and greening pharmaceutical supply chains.

کلیدواژه‌ها English

Closed-Loop Supply Chain Design
Pharmaceutical Products
Product Returns
Green Supply Chain
Cuckoo Search Algorithm

Copyright © Marzieh Mozafari, Jafar Savari

 

License

This article is released under the Creative Commons Attribution (CC BY 4.0) license. Anyone is free to copy, share, translate, and adapt this article for any purpose, whether commercial or non-commercial, as long as proper citation is given to the authors and original publication.

 

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مهندسی سیستم و بهره‌وری
دوره 5، شماره 1 - شماره پیاپی 14
شماره پیاپی 14، فصلنامه بهار
بهار 1404
صفحه 135-153

  • تاریخ دریافت 22 دی 1403
  • تاریخ بازنگری 22 بهمن 1403
  • تاریخ پذیرش 15 اسفند 1403
  • تاریخ اولین انتشار 15 اسفند 1403
  • تاریخ انتشار 01 خرداد 1404